Description

1-(4-Methylphenyl)-6-Oxo-2-Thien-2-Ylpiperidine-3-Carboxylic Acid is a high-purity, non-natural amino acid derivative featuring a piperidone core substituted with thiophene and carboxylic acid functional groups. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to its specific structural motifs.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and protein interactions.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis for clients.
• Academic Research: Used in university laboratories for advanced studies in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	1-(4-Methylphenyl)-6-Oxo-2-Thien-2-Ylpiperidine-3-Carboxylic Acid
CAS No.	855715-10-5
Molecular Formula	C18H17NO3S
Molecular Weight	327.40 g/mol
Synonyms	2-(2-Thienyl)-1-(p-tolyl)-6-oxopiperidine-3-carboxylic acid; 1-(4-Methylphenyl)-6-oxo-2-(thiophen-2-yl)piperidine-3-carboxylic acid; 6-Oxo-1-(4-methylphenyl)-2-(2-thienyl)-3-piperidinecarboxylic acid; 1-(p-Tolyl)-2-(2-thienyl)-6-oxopiperidine-3-carboxylic acid; 855715-10-5; 1-(4-Methylphenyl)-6-oxo-2-(2-thienyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)-6-Oxo-2-Thien-2-Ylpiperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider inert atmosphere protection to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.