Description

4,5-Dichloro-3-Methylthiophene-2-Carboxylic Acid is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which provides reactive sites for further chemical modifications, enabling the creation of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and specialty coatings.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to construct complex thiophene-based molecules.
• Ligand and Catalyst Development: Utilized for creating novel ligands for metal catalysis or as a core structure in catalyst design for asymmetric synthesis.

Basic Information

Product Name	4,5-Dichloro-3-Methylthiophene-2-Carboxylic Acid
CAS No.	854626-34-9
Molecular Formula	C7H4Cl2O2S
Molecular Weight	223.08 g/mol
Synonyms	2-Carboxy-4,5-dichloro-3-methylthiophene; 3-Methyl-4,5-dichlorothiophene-2-carboxylic acid; 4,5-Dichloro-3-methyl-2-thiophenecarboxylic acid; 4,5-Dichloro-3-methylthiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4,5-dichloro-3-methyl-; Dichloromethylthiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4,5-Dichloro-3-Methylthiophene-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.