Description

m-Peg5-Bromide CAS NO 854601-80-2 is a high-purity, functionalized polyethylene glycol derivative featuring a terminal bromide group. This compound is a critical intermediate in the synthesis of complex molecules, enabling precise conjugation and modification. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, bioconjugation, and polymer chemistry.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional molecules to proteins, peptides, or nanoparticles via its reactive bromide terminus.
• Polymer Chemistry: Serves as a functional initiator or monomer for creating tailored PEG-based copolymers with specific end-group functionality.
• Prodrug Synthesis: Facilitates the development of prodrugs by providing a cleavable PEG spacer to improve solubility and pharmacokinetics.
• Surface Modification: Employed to functionalize surfaces and materials with PEG brushes to create non-fouling, biocompatible coatings.
• Cross-linking Agent: Acts as a cross-linker in hydrogel formation and other polymeric network structures.

Basic Information

Product Name	m-Peg5-Bromide
CAS No.	854601-80-2
Molecular Formula	C14H27BrO5
Molecular Weight	355.27 g/mol
Synonyms	2,5,8,11,14-Pentaoxaheptadecan-17-yl Bromide; 1-Bromo-3,6,9,12-tetraoxapentadecane; Br-PEG5-CH3; mPEG5-Br; Methyl-PEG5-bromide; 3,6,9,12-Tetraoxapentadecyl Bromide; Bromo-PEG5-methyl ether; PEG Methyl Ether Bromide (MW ~350)
EINECS	Contact for details

Quality Control

Our m-Peg5-Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or dry conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Bromide Content	≥ 95.0% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.