Description

5-Fluoro-1,3-Dimethyl-1H-Indole-2-Carboxylic Acid is a high-value fluorinated indole derivative, serving as a critical building block in modern synthetic organic chemistry. Its unique structure, featuring a carboxylic acid group and fluorine substitution, makes it an essential intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Employed in the development of organic semiconductors, fluorescent dyes, and other functional materials due to its indole core.
• Academic & Contract Research: Serves as a standard or custom building block in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.
• Peptidomimetics & Bio-conjugation: The carboxylic acid functionality allows for facile coupling to amines, making it useful in designing peptide analogs and bioconjugates.

Basic Information

Product Name	5-Fluoro-1,3-Dimethyl-1H-Indole-2-Carboxylic Acid
CAS No.	854531-33-2
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	5-Fluoro-1,3-dimethylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-fluoro-1,3-dimethyl-; 5-Fluoro-1,3-dimethyl-1H-indole-2-carboxylate; 2-Carboxy-5-fluoro-1,3-dimethylindole; 854531-33-2; 5-Fluoro-1,3-dimethylindole-2-carboxylate; F-DMICA
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-1,3-Dimethyl-1H-Indole-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.