Description

Methyl 2-(Chloromethyl)-5-(2-Methoxy-2-Oxoethyl)-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 854357-39-4. This heterocyclic compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly in kinase inhibitor and antiviral therapeutic classes.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct fused thienopyrimidine scaffolds, which are privileged structures in medicinal chemistry.
• Chemical Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules during process development.

Basic Information

Product Name	Methyl 2-(Chloromethyl)-5-(2-Methoxy-2-Oxoethyl)-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	854357-39-4
Molecular Formula	C13H13ClN2O5S
Molecular Weight	344.77 g/mol
Synonyms	Methyl 2-(chloromethyl)-5-(2-methoxy-2-oxoethyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 3,4-dihydro-2-(chloromethyl)-5-(2-methoxy-2-oxoethyl)-4-oxo-, methyl ester; CAS 854357-39-4; 2-(Chloromethyl)-5-(2-methoxy-2-oxoethyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(Chloromethyl)-5-(2-Methoxy-2-Oxoethyl)-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidine-6-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP-compliant manufacturing processes for our global pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.