Description

4-Methoxy-3-(Trifluoromethoxy)Benzyl Bromide, 97% is a high-purity, functionalized benzyl bromide derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its trifluoromethoxy and methoxy substituents, which introduce unique electronic and steric properties into target molecules, enabling the development of novel materials and active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing novel organic electronic materials, where its aromatic core and substituents contribute to desired photophysical and mesogenic properties.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging the benzyl bromide moiety for facile functionalization.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing aromatic and fluorinated segments into polymers to alter thermal, chemical, or surface properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, where it can be used to attach reporter groups to biomolecules.

Basic Information

Product Name	4-Methoxy-3-(Trifluoromethoxy)Benzyl Bromide, 97%
CAS No.	853771-92-3
Molecular Formula	C9H8BrF3O2
Molecular Weight	285.06 g/mol
Synonyms	1-(Bromomethyl)-4-methoxy-3-(trifluoromethoxy)benzene; 4-Methoxy-3-(trifluoromethoxy)benzyl Bromide; 3-(Trifluoromethoxy)-4-methoxybenzyl Bromide; α-Bromo-4-methoxy-3-(trifluoromethoxy)toluene; (4-Methoxy-3-(trifluoromethoxy)phenyl)methyl Bromide; 853771-92-3; Benzene, 1-(bromomethyl)-4-methoxy-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) are available upon request, detailing results from tests including assay (HPLC), identification (IR, NMR), and control of specified impurities. Our quality management system supports cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged procedures.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.