Description

4-Bromo-3-Chlorobenzenethiol is a versatile organosulfur building block characterized by its reactive thiol (-SH) group and halogen substituents. This compound matters for its utility as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research and development. Industries that need it include fine chemical manufacturers, pharmaceutical R&D labs, and agrochemical companies developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfur heterocycles or thioether linkages.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and chloro groups allow for further functionalization.
• Ligand and Catalyst Preparation: Acts as a starting material for the synthesis of specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of novel monomers or additives for polymers, leveraging the thiol group for click chemistry or polymerization processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and protein interactions.

Basic Information

Product Name	4-Bromo-3-Chlorobenzenethiol
CAS No.	853308-08-4
Molecular Formula	C6H4BrClS
Molecular Weight	223.52 g/mol
Synonyms	3-Chloro-4-bromobenzenethiol; 4-Bromo-3-chlorothiophenol; 1-Bromo-2-chloro-4-mercaptobenzene; Benzenethiol, 4-bromo-3-chloro-; (4-Bromo-3-chlorophenyl)thiol; 853308-08-4; 4-Bromo-3-chloro-benzenethiol
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chlorobenzenethiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.