Description

4-Bromo-3-Nitrobenzenethiol is a specialized aromatic thiol derivative, serving as a versatile building block in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents adjacent to a thiol group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibition or receptor binding.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the nitro and thiol groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, conductive materials, and self-assembled monolayers (SAMs).
• Chemical Biology Probes: Useful for synthesizing probes that study protein function through thiol-reactive or photo-affinity labeling.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	4-Bromo-3-Nitrobenzenethiol
CAS No.	853308-07-3
Molecular Formula	C6H4BrNO2S
Molecular Weight	234.07 g/mol
Synonyms	3-Nitro-4-bromobenzenethiol; 4-Bromo-3-nitrothiophenol; 1-Bromo-2-nitro-6-mercaptobenzene; Benzenethiol, 4-bromo-3-nitro-; 4-Bromo-3-nitrobenzenethiol; 853308-07-3; 4-Br-3-NO2-C6H3SH
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Nitrobenzenethiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.