Description

4-(Bromomethyl)-2-(Trifluoromethyl)Thiazole is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive bromomethyl group and electron-withdrawing trifluoromethyl substituent. It is primarily sought after by research institutions and industrial R&D departments focused on developing new active ingredients, including potential drugs and crop protection agents. Its unique structure makes it an indispensable intermediate for medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, leveraging the biological activity of the thiazole and trifluoromethyl groups.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the pharmaceutical and specialty chemical industries.
• Academic Research: Utilized in universities and research institutes for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(Bromomethyl)-2-(Trifluoromethyl)Thiazole
CAS No.	852854-38-7
Molecular Formula	C5H3BrF3NS
Molecular Weight	246.05 g/mol
Synonyms	2-(Trifluoromethyl)-4-(bromomethyl)thiazole; 4-Bromomethyl-2-trifluoromethylthiazole; Thiazole, 4-(bromomethyl)-2-(trifluoromethyl)-; 852854-38-7; 4-(Bromomethyl)-2-(trifluoromethyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-2-(Trifluoromethyl)Thiazole is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.