Description

(1S,2S,4R,5R,6S)-2-Amino-4-Methylbicyclo[3.1.0]Hexane-2,6-Dicarboxylicacid is a high-purity, stereochemically defined bicyclic amino acid derivative. This compound serves as a critical chiral building block and pharmacological research intermediate for the development of novel therapeutics. It is primarily utilized by pharmaceutical R&D organizations, contract research and manufacturing (CRO/CMO) companies, and academic research institutions focused on neuroscience and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of potential drug candidates targeting neurological disorders.
• Neuroscience Research: Investigation as a potential ligand or modulator for glutamate receptors and transporters.
• Medicinal Chemistry: Building block for creating focused libraries of conformationally restricted amino acid analogs.
• Asymmetric Synthesis: Use as a chiral auxiliary or precursor in stereoselective catalytic processes.
• Biochemical Research: Tool compound for studying enzyme-substrate interactions and metabolic pathways.
• Peptidomimetics: Incorporation into peptide backbones to enhance stability, bioavailability, and biological activity.

Basic Information

Product Name	(1S,2S,4R,5R,6S)-2-Amino-4-Methylbicyclo[3.1.0]Hexane-2,6-Dicarboxylicacid
CAS No.	852679-66-4
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	(1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid; (1S,2S,4R,5R,6S)-2-Amino-4-methyl-2,6-bicyclo[3.1.0]hexanedicarboxylic acid; 2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid (specified stereoisomer); LY-235959 related compound; Glutamate analogue; Bicyclic glutamate derivative
EINECS	Contact for details

Quality Control

Our (1S,2S,4R,5R,6S)-2-Amino-4-Methylbicyclo[3.1.0]Hexane-2,6-Dicarboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.