Description

(3-Bromo-1-Propyn-1-Yl)Cyclopropane is a specialized halogenated alkyne building block featuring a reactive cyclopropane ring. This compound matters for its unique structural motif, which enables the synthesis of complex molecular architectures in advanced organic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of bioactive molecules, particularly those containing strained ring systems or alkyne functionalities for click chemistry.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive bromoalkyne group for further functionalization.
• Material Science Research: Serves as a precursor for advanced polymers or metal-organic frameworks (MOFs) where the cyclopropane and alkyne groups impart specific mechanical or electronic properties.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form complex carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands or organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Employed to create tagged molecules or probes for studying biological processes due to its bio-orthogonal reactivity.

Basic Information

Product Name	(3-Bromo-1-Propyn-1-Yl)Cyclopropane
CAS No.	852526-08-0
Molecular Formula	C6H7Br
Molecular Weight	159.03 g/mol
Synonyms	3-Bromoprop-1-yn-1-ylcyclopropane; Cyclopropane, (3-bromo-1-propyn-1-yl)-; 1-Cyclopropyl-3-bromoprop-1-yne; (3-Bromoprop-1-ynyl)cyclopropane; Bromo(cyclopropylethynyl)methane
EINECS	Contact for details

Quality Control

Our (3-Bromo-1-Propyn-1-Yl)Cyclopropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.