Description

(4-Mercaptophenyl)Carbamic Acid tert-Butyl Ester is a specialized organosulfur compound featuring a protected thiol group. This chemical is a critical building block in organic synthesis, valued for its role as a key intermediate in the development of pharmaceuticals and advanced materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or disulfide linkages.
• Peptide Chemistry & Bioconjugation: Used for introducing protected thiol functionalities into peptides or proteins for site-specific labeling and cross-linking applications.
• Ligand Synthesis for Catalysis: Serves as a starting material for creating sulfur-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of novel polymers, functionalized surfaces, and self-assembled monolayers (SAMs).
• Agrochemical Synthesis: An intermediate in the production of certain herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized to create probes for studying enzyme activity or protein function where a controlled thiol group is required.

Basic Information

Item	Detail
Product Name	(4-Mercaptophenyl)Carbamic Acid tert-Butyl Ester
CAS No.	852448-31-8
Molecular Formula	C12H17NO2S
Molecular Weight	239.33 g/mol
Synonyms	tert-Butyl (4-mercaptophenyl)carbamate; N-Boc-4-aminobenzenethiol; 4-((tert-Butoxycarbonyl)amino)benzenethiol; 4-Mercaptoaniline N-Boc derivative; Boc-4-aminothiophenol; 4-Aminobenzenethiol, N-Boc protected; (4-Mercaptophenyl)carbamic acid 1,1-dimethylethyl ester; 4-Thio-Boc-aniline
EINECS	Contact for details

Quality Control

Our (4-Mercaptophenyl)Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.