Description

2-Chloro-n-[3-Cyano-1-(4-Fluorobenzyl)-4,5-Dimethyl-1H-Pyrrol-2-Yl]Acetamide is a high-purity, advanced pharmaceutical intermediate with a complex pyrrole-based molecular structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers engaged in synthesizing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales under cGMP conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and proprietary client development programs.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2-Chloro-n-[3-Cyano-1-(4-Fluorobenzyl)-4,5-Dimethyl-1H-Pyrrol-2-Yl]Acetamide
CAS No.	852400-31-8
Molecular Formula	C₁₇H₁₇ClFN₃O
Molecular Weight	333.79 g/mol
Synonyms	2-Chloro-N-[3-cyano-1-[(4-fluorophenyl)methyl]-4,5-dimethyl-1H-pyrrol-2-yl]acetamide; 2-Chloroacetamide, N-[3-cyano-1-(4-fluorobenzyl)-4,5-dimethyl-1H-pyrrol-2-yl]-; 852400-31-8; 1H-Pyrrole-2-acetamide, 1-[(4-fluorophenyl)methyl]-3-cyano-4,5-dimethyl-N-(chloroacetyl)-; 2-Chloro-N-(3-cyano-1-(4-fluorobenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)acetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-[3-Cyano-1-(4-Fluorobenzyl)-4,5-Dimethyl-1H-Pyrrol-2-Yl]Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.