Description

5-(4-Bromophenyl)-1-Methyl-1H-Imidazole-2-Thiol is a high-value brominated heterocyclic building block, primarily used as a key intermediate in advanced organic synthesis. Its core value lies in its versatile reactivity, enabling the construction of complex molecular architectures for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing new active ingredients, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the (4-bromophenyl) moiety into more complex molecules.
• Bioconjugation & Probe Development: Useful for creating chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	5-(4-Bromophenyl)-1-Methyl-1H-Imidazole-2-Thiol
CAS No.	852388-69-3
Molecular Formula	C10H9BrN2S
Molecular Weight	269.16 g/mol
Synonyms	1-Methyl-5-(4-bromophenyl)-1H-imidazole-2-thiol; 2-Mercapto-1-methyl-5-(4-bromophenyl)imidazole; 5-(4-Bromophenyl)-1-methyl-1H-imidazole-2-thione; 1-Methyl-5-(p-bromophenyl)imidazole-2-thiol; 852388-69-3; 5-(4-Bromophenyl)-1-methylimidazole-2-thiol
EINECS	Contact for details

Quality Control

Our 5-(4-Bromophenyl)-1-Methyl-1H-Imidazole-2-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.