Description

2-(4-(2-Furylcarbonyl)Piperazinyl)-1-Indol-3-Ylethane-1,2-Dione CAS NO 852367-25-0 is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within the fields of oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates with targeted biological activity.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead molecules.
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs), particularly those targeting kinase inhibition or receptor modulation.
• Biochemical Tool Compound: Utilized in academic and industrial research to study biochemical pathways and validate novel drug targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client-specific discovery programs.

Basic Information

Product Name	2-(4-(2-Furylcarbonyl)Piperazinyl)-1-Indol-3-Ylethane-1,2-Dione
CAS No.	852367-25-0
Molecular Formula	C19H17N3O4
Molecular Weight	351.36 g/mol
Synonyms	1H-Indole-3-ethanedione, 2-[4-(2-furoyl)-1-piperazinyl]-; 2-[4-(2-Furoyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethane-1,2-dione; 2-(4-(2-Furoyl)piperazin-1-yl)-1-(1H-indol-3-yl)ethanedione; Furoylpiperazinyl indole diketone; (1H-Indol-3-yl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]ethane-1,2-dione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive R&D applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Quality is assured through analytical techniques including HPLC, NMR, and mass spectrometry, supporting compliance with cGMP guidelines where required for early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.