Description

2-(Chloromethyl)-6-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One is a high-value heterocyclic building block and key synthetic intermediate. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought after by pharmaceutical R&D, agrochemical innovators, and specialty chemical synthesis units for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides with specific modes of action.
• Organic Light-Emitting Diodes (OLEDs): Serves as a core structure for electron-transport or emissive layer materials.
• Material Science: Building block for advanced polymers and liquid crystals with tailored electronic properties.
• Chemical Biology: Useful as a molecular probe or tag due to its reactive chloromethyl group.
• Academic & Contract Research: Employed in methodological studies and custom synthesis projects.

Basic Information

Product Name	2-(Chloromethyl)-6-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	852218-16-7
Molecular Formula	C13H9ClN2OS
Molecular Weight	276.74 g/mol
Synonyms	2-(Chloromethyl)-6-phenyl-3H-thieno[2,3-d]pyrimidin-4-one; 6-Phenyl-2-(chloromethyl)thieno[2,3-d]pyrimidin-4(3H)-one; 852218-16-7; Thieno[2,3-d]pyrimidin-4(3H)-one, 2-(chloromethyl)-6-phenyl-; CAS 852218-16-7
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-6-Phenylthieno[2,3-D]Pyrimidin-4(3H)-One adheres to stringent in-process controls and final batch release testing. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports cGMP compliance for pharmaceutical applications, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.