Description

5-Bromo-1H-T-Butoxycarbonyl-Indole-3-Carboxylic Acid is a high-purity, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive carboxylic acid group and a protected indole nitrogen, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific indole-based structures.
• Peptide Mimetics & Conjugation: The carboxylic acid moiety allows for coupling reactions to create peptide-like molecules or for bioconjugation strategies.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers with unique electronic or photophysical properties.
• Chemical Biology Probes: Utilized to develop fluorescent tags or affinity probes for studying biological systems and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic routes in heterocyclic chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-1H-T-Butoxycarbonyl-Indole-3-Carboxylic Acid
CAS No.	852180-98-4
Molecular Formula	C₁₄H₁₄BrNO₄
Molecular Weight	340.17 g/mol
Synonyms	5-Bromo-1-(tert-Butoxycarbonyl)-1H-indole-3-carboxylic acid; 5-Bromo-1-Boc-indole-3-carboxylic acid; 5-Bromo-1H-Indole-3-carboxylic acid, 1-(1,1-dimethylethyl) ester; Boc-5-Bromo-3-indolecarboxylic acid; 5-Br-1-Boc-indole-3-COOH; tert-Butyl 5-bromo-3-carboxyindole-1-carboxylate; 852180-98-4; 5-Bromoindole-3-carboxylic acid Boc-protected
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with comprehensive identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents. We can support development projects with custom purity grades and analytical validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.