Description

Ethyl 4-Methyl-2-(n-Boc-Piperidin-4-Yl)Thiazol-5-Yl Carboxylate is a high-value, protected heterocyclic building block featuring both a thiazole and a tert-butoxycarbonyl (Boc)-protected piperidine moiety. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with potential biological activity. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used as a core structural element for constructing compound libraries via parallel and combinatorial chemistry for high-throughput screening (HTS).
• Protease Inhibitor Research: The Boc-protected piperidine-thiazole core is a valuable motif in the design and synthesis of protease and kinase inhibitors.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the custom production of advanced intermediates under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Ethyl 4-Methyl-2-(n-Boc-Piperidin-4-Yl)Thiazol-5-Yl Carboxylate
CAS No.	852180-50-8
Molecular Formula	C17H26N2O4S
Molecular Weight	354.47 g/mol
Synonyms	Ethyl 4-Methyl-2-(1-Boc-4-piperidinyl)-5-thiazolecarboxylate; 2-(1-tert-Butoxycarbonyl-4-piperidinyl)-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester; 1-Boc-4-(5-Ethoxycarbonyl-4-methylthiazol-2-yl)piperidine; 852180-50-8; Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-4-methyl-1,3-thiazole-5-carboxylate; 4-Methyl-2-(N-Boc-piperidin-4-yl)thiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methyl-2-(n-Boc-Piperidin-4-Yl)Thiazol-5-Yl Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.