Description

n-Palmitoyl-D31-D-Erythro-Sphingosine is a deuterium-labeled, saturated fatty acid derivative of sphingosine, serving as a critical internal standard and tracer in advanced lipidomics and metabolic research. This high-purity, isotopically labeled compound is essential for achieving precise quantification and tracking of sphingolipid metabolism in complex biological systems. It is primarily utilized by researchers and analytical laboratories in the pharmaceutical, biotechnology, and life science sectors for mass spectrometry-based assays, drug discovery, and biomarker studies.

Application

• Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS/MS and GC-MS analyses for sphingolipids, ensuring accurate measurement of endogenous levels.
• Metabolic Pathway Tracing: Enables the study of sphingolipid biosynthesis, turnover, and degradation pathways in cell culture and in vivo models.
• Drug Discovery & Pharmacokinetics: Supports ADME (Absorption, Distribution, Metabolism, Excretion) studies for drug candidates targeting sphingolipid-related pathways.
• Biomarker Research: Facilitates the development and validation of clinical assays for disease biomarkers associated with sphingolipid imbalances.
• Lipidomics Reference Material: Provides a stable, isotopically distinct signal for profiling and identifying complex lipid species in lipidomic screens.
• Quality Control in Diagnostic Kits: Serves as a calibrant or control in commercial diagnostic kits for neurological and metabolic disorders.

Basic Information

Product Name	n-Palmitoyl-D31-D-Erythro-Sphingosine
CAS No.	852043-41-5
Molecular Formula	C34D31H37NO3
Molecular Weight	~539.8 g/mol
Synonyms	N-(Hexadecanoyl)-D-erythro-sphingosine-d31; D-erythro-C16-Ceramide-d31; Palmitoyl-D31-sphingosine; N-Palmitoyl-D-erythro-sphingosine (d31); Deuterated C16-Ceramide; Sphingosine-d31 palmitate; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-Palmitate-d31
EINECS	Contact for details

Quality Control

Our n-Palmitoyl-D31-D-Erythro-Sphingosine is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content. We adhere to relevant industry standards for research chemicals, ensuring reliable batch-to-batch consistency and traceability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.