Description

Monepantel Sulfoxide is a key intermediate metabolite of the anthelmintic drug Monepantel, playing a critical role in its pharmacological activity. This compound is essential for the research and development of novel veterinary parasiticides targeting resistant nematode strains. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and manufacturers of active pharmaceutical ingredients (APIs) for veterinary medicine.

Application

• Veterinary Pharmaceutical Intermediate: A crucial metabolite and synthetic intermediate in the production of the anthelmintic drug Monepantel.
• Anthelmintic Research: Used in biochemical and pharmacological studies to understand the mode of action and metabolism of amino-acetonitrile derivative (AAD) anthelmintics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in veterinary drug manufacturing.
• Metabolite Profiling: Employed in the development and validation of analytical methods (e.g., HPLC, LC-MS) for drug residue and pharmacokinetic studies.
• API Synthesis: A key building block in the multi-step synthesis of Monepantel and related anthelmintic compounds.
• Veterinary Parasitology: Used in *in vitro* and *in vivo* studies to evaluate efficacy against gastrointestinal nematodes in livestock.

Basic Information

Product Name	Monepantel Sulfoxide
CAS No.	851976-72-2
Molecular Formula	C₁₉H₂₁F₃N₂O₂S
Molecular Weight	398.44 g/mol
Synonyms	Monepantel Sulfoxide; Zolvix Sulfoxide; (RS)-4-[(2-Cyano-2-methylsulfinyl-1-phenylethyl)carbamoyl]-2-trifluoromethylbenzonitrile; 4-[(2-Cyano-1-phenylethyl)sulfinyl]-2-(trifluoromethyl)benzonitrile; AAD-1566 Sulfoxide; 2-[(4-Cyano-2-trifluoromethylbenzoyl)amino]-2-phenyl-1-cyanoethyl methyl sulfoxide
EINECS	Contact for details

Quality Control

Our Monepantel Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.