Description

Methyl 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate CAS NO 851784-90-2 is a high-purity, synthetically versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized tetrahydroisoquinoline scaffold, which serves as a critical intermediate for the development of novel pharmacologically active compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential building block for advanced organic materials and ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	Methyl 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate
CAS No.	851784-90-2
Molecular Formula	C11H11Cl2NO2
Molecular Weight	260.12 g/mol
Synonyms	Methyl 5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carboxylate; 6-Carbomethoxy-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline; 5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid methyl ester; 851784-90-2; Methyl 5,7-dichlorotetrahydroisoquinoline-6-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.