Description

2(1H)-Isoquinolinecarboxylic Acid, 5,7-Dichloro-3,4-Dihydro-6-Hydroxy-, 1,1-Dimethylethyl Ester is a high-purity, synthetically valuable chemical intermediate characterized by its unique halogenated isoquinoline structure. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its dichloro and hydroxy functional groups.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science: Potential intermediate for synthesizing specialized ligands, catalysts, or organic electronic materials.
• Chemical Biology Probe Development: Utilized in creating molecular probes for studying enzyme function and biological pathways due to its modifiable scaffold.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 5,7-Dichloro-3,4-Dihydro-6-Hydroxy-, 1,1-Dimethylethyl Ester
CAS No.	851784-76-4
Molecular Formula	C15H15Cl2NO3
Molecular Weight	328.19 g/mol
Synonyms	5,7-Dichloro-3,4-dihydro-6-hydroxy-2(1H)-isoquinolinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 5,7-dichloro-3,4-dihydro-6-hydroxy-1-oxo-1H-isoquinoline-2-carboxylate; 5,7-Dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylic acid tert-butyl ester; 2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-hydroxy-, 1,1-dimethylethyl ester; tert-Butyl 5,7-dichloro-6-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate; CAS 851784-76-4
EINECS	Contact for details

Quality Control

Our 2(1H)-Isoquinolinecarboxylic Acid, 5,7-Dichloro-3,4-Dihydro-6-Hydroxy-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.