Description

2-(5-Bromo-Thiophen-2-Yl)-2,3-Dihydro-Benzofuran-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its fused benzofuran-thiophene heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel small-molecule drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor in the research of organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-(5-Bromo-Thiophen-2-Yl)-2,3-Dihydro-Benzofuran-5-Carbonitrile
CAS No.	851777-32-7
Molecular Formula	C₁₃H₈BrNOS
Molecular Weight	306.18 g/mol
Synonyms	5-Cyano-2-(5-bromo-2-thienyl)-2,3-dihydrobenzofuran; 2,3-Dihydro-2-(5-bromo-2-thienyl)-5-benzofurancarbonitrile; 2-(5-Bromothiophen-2-yl)-2,3-dihydro-1-benzofuran-5-carbonitrile; 851777-32-7; 2-(5-Bromo-2-thienyl)-2,3-dihydro-5-benzofurancarbonitrile
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-Thiophen-2-Yl)-2,3-Dihydro-Benzofuran-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.