Description

Ethyl 1-Methyl-5-(Difluoromethyl)-1H-Pyrazole-4-Carboxylate is a high-purity pyrazole derivative serving as a critical advanced intermediate in modern synthetic chemistry. This compound is valued for its unique difluoromethylated pyrazole core, which imparts desirable physicochemical properties to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, where the difluoromethyl group enhances biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold in organic synthesis for constructing complex heterocyclic compounds in academic and industrial labs.
• Material Science Precursor: Potential intermediate in the development of specialty chemicals and functional materials requiring fluorinated heterocycles.

Basic Information

Product Name	Ethyl 1-Methyl-5-(Difluoromethyl)-1H-Pyrazole-4-Carboxylate
CAS No.	851725-98-9
Molecular Formula	C8H10F2N2O2
Molecular Weight	204.18 g/mol
Synonyms	Ethyl 1-methyl-5-(difluoromethyl)-1H-pyrazole-4-carboxylate; 1-Methyl-5-(difluoromethyl)-1H-pyrazole-4-carboxylic acid ethyl ester; 851725-98-9; 5-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 5-(difluoromethyl)-1-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Methyl-5-(Difluoromethyl)-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to fluoride/strong alkali and high volatility, keep away from incompatible materials and ensure containers are securely sealed.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.