Description

Ethyl 2-(5-Fluoro-2-Methyl-1H-Indol-1-Yl)Acetate is a high-purity fluorinated indole derivative, serving as a critical pharmaceutical intermediate and research chemical for advanced organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in medicinal chemistry. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and high-throughput screening libraries due to its privileged indole scaffold.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced fungicides and plant growth regulators.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions and other advanced transformations to introduce complex fluorinated indole motifs.
• Biochemical Tool Compound: Potential use in developing fluorescent probes or enzyme inhibitors for biochemical assays.
• Material Science Precursor: Can be utilized in the synthesis of specialized organic electronic materials or ligands for catalysis.

Basic Information

Product Name	Ethyl 2-(5-Fluoro-2-Methyl-1H-Indol-1-Yl)Acetate
CAS No.	851460-85-0
Molecular Formula	C₁₃H₁₄FNO₂
Molecular Weight	235.26 g/mol
Synonyms	1H-Indole-1-acetic acid, 5-fluoro-2-methyl-, ethyl ester; Ethyl (5-fluoro-2-methyl-1H-indol-1-yl)acetate; 5-Fluoro-2-methyl-1H-indol-1-ylacetic Acid Ethyl Ester; 851460-85-0; 5-Fluoro-2-methylindol-1-ylacetic acid ethyl ester; Ethyl 5-fluoro-2-methylindole-1-acetate; 1-Acetic acid, 5-fluoro-2-methylindol-1-yl, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Fluoro-2-Methyl-1H-Indol-1-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for pharmaceutical and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.