Description

5-Piperazin-1-Ylthiophene-2-Carbaldehyde is a high-purity heterocyclic building block featuring a thiophene core functionalized with a piperazine and an aldehyde group. This compound is a critical intermediate in modern pharmaceutical research and development, enabling the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products.
• Material Science: Serves as a precursor for functionalized polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific projects.
• Academic Research: Used in universities and research institutes for methodological studies and novel heterocycle chemistry.

Basic Information

Product Name	5-Piperazin-1-Ylthiophene-2-Carbaldehyde
CAS No.	851208-08-7
Molecular Formula	C9H12N2OS
Molecular Weight	196.27 g/mol
Synonyms	5-(Piperazin-1-yl)thiophene-2-carboxaldehyde; 2-Formyl-5-piperazin-1-ylthiophene; 5-(1-Piperazinyl)-2-thiophenecarboxaldehyde; Thiophene-2-carboxaldehyde, 5-(1-piperazinyl)-; 851208-08-7; 5-Piperazin-1-yl-thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Piperazin-1-Ylthiophene-2-Carbaldehyde is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment to guarantee reproducible results and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.