Description

trans-4-(2-Nitrovinyl)Indole CAS NO 851192-48-8 is a high-purity, synthetically valuable indole derivative characterized by its nitrovinyl functional group. This compound serves as a versatile and critical advanced pharmaceutical intermediate and building block in organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex molecules with potential biological activity, including kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used as a building block for developing new crop protection agents and pesticides.
• Organic Synthesis & Material Science: Serves as a versatile synthon for constructing complex heterocyclic frameworks and functional materials.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical reactions, such as cycloadditions and cross-coupling reactions.
• Bioconjugation & Probe Development: The reactive nitrovinyl group can be utilized for selective bioconjugation or in the creation of fluorescent probes and sensors.

Basic Information

Product Name	trans-4-(2-Nitrovinyl)Indole
CAS No.	851192-48-8
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	4-[(E)-2-Nitroethenyl]-1H-indole; (E)-4-(2-Nitrovinyl)-1H-indole; 1H-Indole, 4-[(E)-2-nitroethenyl]-; trans-4-(2-Nitrovinyl)-1H-indole; 4-(2-Nitrovinyl)indole; 4-Nitrovinylindole; 4-[(E)-2-Nitrovinyl]indole; 4-(trans-2-Nitrovinyl)indole
EINECS	Contact for details

Quality Control

Our trans-4-(2-Nitrovinyl)Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and other analytical techniques. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.