Description

5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key building block in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Serves as a key building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis methodology development.

Basic Information

Product Name	5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole-3-Carboxylic Acid
CAS No.	850893-02-6
Molecular Formula	C₁₃H₁₃BrN₂O₃
Molecular Weight	325.16 g/mol
Synonyms	5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-3-carboxylic acid; 5-Bromo-1-(tetrahydropyran-2-yl)-1H-indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 5-bromo-1-(tetrahydro-2H-pyran-2-yl)-; 5-Bromo-1-THP-indazole-3-carboxylic acid; 5-Br-1-THP-1H-indazole-3-COOH; 850893-02-6; THP-protected 5-bromoindazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.