Description

4-Nitro-1-(Phenylsulfonyl)-1H-Indole is a high-value, functionalized indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both nitro and phenylsulfonyl protecting groups, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and CNS-targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the indole scaffold for biological activity.
• Material Science: Serves as a monomer or functional unit in the research of organic electronic materials and specialty polymers.
• Academic & R&D: Employed in methodological studies and as a standard reagent for novel cross-coupling and functionalization reactions in organic synthesis laboratories.
• Chemical Biology: Utilized as a probe or tagging molecule in the study of biological pathways and enzyme inhibition.

Basic Information

Product Name	4-Nitro-1-(Phenylsulfonyl)-1H-Indole
CAS No.	850655-62-8
Molecular Formula	C₁₄H₁₀N₂O₄S
Molecular Weight	302.31 g/mol
Synonyms	1-(Benzenesulfonyl)-4-nitro-1H-indole; 4-Nitro-1H-indole-1-sulfonic acid phenyl ester; 4-Nitroindole-1-phenylsulfone; N-(Phenylsulfonyl)-4-nitroindole; 1-(Phenylsulfonyl)-4-nitroindole; 4-Nitro-1-(phenylsulfonyl)indole; 850655-62-8; 4-Nitro-1H-indole, 1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Nitro-1-(Phenylsulfonyl)-1H-Indole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.