Description

4-(Thiazoline-3-Carbonyl)Benzeneboronic Acid is a specialized organoboron compound that serves as a valuable synthetic intermediate. Its molecular architecture, featuring both a boronic acid and a thiazoline-carbonyl moiety, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a critical boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the development of compound libraries for identifying new drug candidates.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein interactions.

Basic Information

Product Name	4-(Thiazoline-3-Carbonyl)Benzeneboronic Acid
CAS No.	850589-33-2
Molecular Formula	C12H12BNO3S
Molecular Weight	261.11 g/mol
Synonyms	4-(Thiazoline-3-carbonyl)phenylboronic acid; [4-(1,3-Thiazolin-3-ylcarbonyl)phenyl]boronic acid; Benzeneboronic acid, 4-(3-thiazolinecarbonyl)-; 4-(1,3-Thiazoline-3-carbonyl)benzeneboronic acid; 4-(Thiazolin-3-oyl)benzeneboronic acid; 4-(3-Thiazolinecarbonyl)phenylboronic Acid; B-[4-(1,3-Thiazoline-3-carbonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(Thiazoline-3-Carbonyl)Benzeneboronic Acid is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.