Description

5-Benzyloxy-1-Boc-Indole-2-Boronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in modern organic synthesis, enabling the formation of complex molecular architectures through efficient cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Suzuki-Miyaura Cross-Coupling Reactions: Enables the formation of carbon-carbon bonds to attach diverse aryl or heteroaryl groups to the indole scaffold, a fundamental step in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the indole core structure.
• Material Science Exploration: Serves as a monomer or building block for creating novel organic electronic materials and functional polymers.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Benzyloxy-1-Boc-Indole-2-Boronic Acid
CAS No.	850568-62-6
Molecular Formula	C20H22BNO5
Molecular Weight	367.21 g/mol
Synonyms	1-Boc-5-(Benzyloxy)indole-2-boronic Acid; 5-(Benzyloxy)-1-[(tert-butoxy)carbonyl]-1H-indole-2-boronic Acid; tert-Butyl 5-(benzyloxy)-2-borono-1H-indole-1-carboxylate; 5-Benzyloxy-1-Boc-indole-2-boronic Acid Pinacol Ester (common derivative); 1H-Indole-2-boronic acid, 5-(phenylmethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-; BOC-5-OBn-Indole-2-Boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-Benzyloxy-1-Boc-Indole-2-Boronic Acid is manufactured and tested under strict quality management systems to ensure consistent purity and performance. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.