Description

(3-Amino-5-Methoxycarbonyl)Benzeneboronic Acid Pinacol Ester Hydrochloride is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and the development of advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex aromatic structures.
• Material Science: Employed in the synthesis of organic electronic materials, including polymers and small molecules for OLEDs and sensors.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of probes and inhibitors for biological target studies.
• Catalyst Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	(3-Amino-5-Methoxycarbonyl)Benzeneboronic Acid Pinacol Ester Hydrochloride
CAS No.	850567-50-9
Molecular Formula	C15H23BClNO4
Molecular Weight	327.61 g/mol
Synonyms	3-Amino-5-(methoxycarbonyl)benzeneboronic acid pinacol ester hydrochloride; 5-(Aminomethyl)-2-methoxycarbonylphenylboronic acid pinacol ester HCl; 3-Carbomethoxy-5-aminophenylboronic acid pinacol ester hydrochloride; Methyl 3-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate hydrochloride; 850567-50-9; Boronic acid, B-[3-amino-5-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester, hydrochloride; (3-Amino-5-methoxycarbonylphenyl)boronic acid pinacol ester HCl
EINECS	Contact for details

Quality Control

Every batch of (3-Amino-5-Methoxycarbonyl)Benzeneboronic Acid Pinacol Ester Hydrochloride undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols include HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.