Description

n-(3-Bromopropyl) 3-Boronobenzamide is a specialized organoboron compound featuring both a bromopropyl linker and a benzamide group. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules, particularly those targeting boron neutron capture therapy (BNCT) and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules, especially boron-containing drug candidates for oncology and other therapeutic areas.
• Boron Neutron Capture Therapy (BNCT): Serves as a critical building block for developing novel boron delivery agents used in targeted cancer radiation therapy.
• Protease Inhibitor Development: Used in research and development of enzyme inhibitors, leveraging the boronic acid moiety's ability to form reversible covalent bonds with active sites.
• Agrochemical Synthesis: Employed in the creation of new-generation pesticides and herbicides that incorporate boron for enhanced efficacy.
• Materials Science: Acts as a monomer or cross-linking agent in the synthesis of advanced polymers, resins, and functional materials.
• Organic Synthesis & Catalysis: Utilized in Suzuki-Miyaura and other cross-coupling reactions as a functionalized arylboronic acid derivative.

Basic Information

Product Name	n-(3-Bromopropyl) 3-Boronobenzamide
CAS No.	850567-42-9
Molecular Formula	C10H13BBrNO2
Molecular Weight	270.93 g/mol
Synonyms	3-[(3-Bromopropanoyl)amino]benzeneboronic acid; 3-Boronobenzamide, N-(3-bromopropyl)-; 3-(3-Bromopropanamido)phenylboronic acid; B-[3-[(3-Bromopropanoyl)amino]phenyl]boronic acid; N-(3-Bromopropionyl)-3-aminophenylboronic acid; 850567-42-9; AKOS025310626; AS-80511
EINECS	Contact for details

Quality Control

Our n-(3-Bromopropyl) 3-Boronobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.