Description

3-(2-Thiazolyl)Aminocarbonylphenylboronic Acid is a specialized organoboron compound featuring a phenylboronic acid core functionalized with a thiazole-containing amide group. This unique structure makes it a valuable building block in modern synthetic chemistry, particularly for the development of pharmaceuticals and advanced materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions and as a precursor for bioactive molecule synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting kinase inhibition or requiring complex biaryl structures.
• Agrochemical Synthesis: Used in the creation of novel active ingredients for crop protection products, leveraging its boronic acid functionality for carbon-carbon bond formation.
• Material Science Research: Serves as a monomer or functionalizing agent in the synthesis of organic electronic materials, polymers, or metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid partner for palladium-catalyzed coupling reactions to construct biaryl and heterobiaryl systems.
• Chemical Biology & Proteomics: Potential use in designing probes or inhibitors that interact with biological thiols or as a handle for bioconjugation strategies.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new synthetic pathways.

Basic Information

Product Name	3-(2-Thiazolyl)Aminocarbonylphenylboronic Acid
CAS No.	850567-34-9
Molecular Formula	C10H9BN2O3S
Molecular Weight	248.07 g/mol
Synonyms	[3-[(1,3-Thiazol-2-yl)carbamoyl]phenyl]boronic acid; 3-(Thiazol-2-ylcarbamoyl)phenylboronic acid; 2-[(3-Boronophenyl)carbonyl]amino-1,3-thiazole; 3-(1,3-Thiazol-2-ylcarbamoyl)benzeneboronic acid; Boronic acid, B-[3-[(2-thiazolylamino)carbonyl]phenyl]-; 3-Carbamoylphenylboronic acid thiazol-2-yl derivative; Amide of 3-boronobenzoic acid with 2-aminothiazole
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Thiazolyl)Aminocarbonylphenylboronic Acid is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with precise specifications and high purity standards essential for research and scale-up. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.