Description

2-tert-Butoxycarbonylaminothiazole-4-Carboxylic Acid Methyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for peptide-mimetic and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiazole-containing drug candidates, including protease inhibitors and kinase inhibitors.
• Peptidomimetic Synthesis: Used to incorporate the thiazole heterocycle into peptide backbones, modifying biological activity and stability.
• Agrochemical Research: Serves as a building block for developing new fungicides and herbicides with novel modes of action.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Potential monomer or intermediate for synthesizing specialized polymers and functional materials.

Basic Information

Product Name	2-tert-Butoxycarbonylaminothiazole-4-Carboxylic Acid Methyl Ester
CAS No.	850429-62-8
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	Boc-Amino-Thz-OMe; Methyl 2-((tert-Butoxycarbonyl)amino)-1,3-thiazole-4-carboxylate; 2-(Boc-amino)-4-(methoxycarbonyl)thiazole; 2-[(tert-Butoxycarbonyl)amino]-4-(methoxycarbonyl)thiazole; 2-(tert-Butoxycarbonylamino)thiazole-4-carboxylic acid methyl ester; 2-(Boc-amino)thiazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-2-(Boc-amino)thiazole; 850429-62-8
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxycarbonylaminothiazole-4-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.