Description

5-Bromo-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a brominated thiazole core with a trifluoromethylphenyl group, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and trifluoromethyl motifs.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as organic semiconductors, liquid crystals, and fluorescent dyes.
• Chemical Biology Probe: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromo-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole
CAS No.	850375-27-8
Molecular Formula	C11H7BrF3NS
Molecular Weight	322.14 g/mol
Synonyms	5-Bromo-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole; 2-(4-Trifluoromethylphenyl)-5-bromo-4-methylthiazole; 5-Bromo-4-methyl-2-(4-trifluoromethylphenyl)thiazole; 850375-27-8; 5-Bromo-4-methyl-2-(α,α,α-trifluoro-p-tolyl)thiazole; 4-Methyl-5-bromo-2-(4-trifluoromethylphenyl)thiazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methyl-2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.