Description

1-(tert-Butyl) 6-Methyl 3-Iodo-1H-Indole-1,6-Dicarboxylate is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of iodine and carboxylate protecting groups, enabling selective cross-coupling reactions and further functionalization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the study of biological pathways.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic routes in university and industrial research labs.

Basic Information

Item	Detail
Product Name	1-(tert-Butyl) 6-Methyl 3-Iodo-1H-Indole-1,6-Dicarboxylate
CAS No.	850374-94-6
Molecular Formula	C15H16INO4
Molecular Weight	401.20 g/mol
Synonyms	3-Iodo-1H-indole-1,6-dicarboxylic acid 1-tert-butyl 6-methyl ester; 1-(tert-Butoxycarbonyl)-6-(methoxycarbonyl)-3-iodoindole; 1-Boc-6-OMe-3-iodoindole; tert-Butyl 6-(methoxycarbonyl)-3-iodo-1H-indole-1-carboxylate; 3-Iodoindole-1,6-dicarboxylate derivative; 850374-94-6; 1-tert-Butyl 6-methyl 3-iodo-1H-indole-1,6-dicarboxylate
EINECS	Contact for details

Quality Control

Our production of 1-(tert-Butyl) 6-Methyl 3-Iodo-1H-Indole-1,6-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.