Description

5-Bromo-3-Iodoindole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, multi-halogenated indole derivative serving as a critical building block in advanced organic synthesis. This compound is specifically engineered to provide a reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel drug candidates, especially in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides and fungicides with specific modes of action.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and proteomics research due to its reactive halogen sites.
• Academic & Contract Research: A valuable reagent for methodology development in cross-coupling reactions and indole chemistry.

Basic Information

Product Name	5-Bromo-3-Iodoindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	850349-72-3
Molecular Formula	C13H13BrINO2
Molecular Weight	422.06 g/mol
Synonyms	tert-Butyl 5-bromo-3-iodo-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 5-bromo-3-iodo-, 1,1-dimethylethyl ester; 5-Bromo-3-iodo-1H-indole-1-carboxylic acid tert-butyl ester; 5-Br-3-I-indole-1-COOtBu; BOC-Protected 5-Bromo-3-Iodoindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodoindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We adhere to cGMP principles where applicable, and all products are supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.