Description

4-Bromo-5,6,7,8-tetrahydroisoquinoline is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmaceutical compounds, particularly in medicinal chemistry research targeting central nervous system and other therapeutic areas. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those with tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing novel active ingredients with potential herbicidal or insecticidal properties.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploratory organic synthesis in academic and industrial research settings.

Basic Information

Product Name	4-Bromo-5,6,7,8-tetrahydroisoquinoline
CAS No.	850349-00-7
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	4-Bromo-5,6,7,8-tetrahydroisoquinoline; 5,6,7,8-Tetrahydro-4-bromoisoquinoline; 4-Bromotetrahydroisoquinoline; Isoquinoline, 4-bromo-5,6,7,8-tetrahydro-; 850349-00-7
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,6,7,8-tetrahydroisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.