Description

1(2H)-Isoquinolinone, 7-Fluoro-6-Hydroxy- is a high-purity fluorinated isoquinolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel bioactive compounds, particularly in medicinal chemistry. This product is primarily needed by research institutions and pharmaceutical manufacturers developing next-generation therapeutics, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and neurology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated isoquinolinone core.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds in organic synthesis.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, leveraging its specific molecular interactions.
• Agrochemical Development: Intermediate in the research and development of new, high-performance crop protection agents.

Basic Information

Product Name	1(2H)-Isoquinolinone, 7-Fluoro-6-Hydroxy-
CAS No.	850340-95-3
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	7-Fluoro-6-hydroxy-1(2H)-isoquinolinone; 7-Fluoro-6-hydroxyisoquinolin-1(2H)-one; 6-Hydroxy-7-fluoro-1,2-dihydroisoquinolin-1-one; 7-Fluoro-6-hydroxy-1,2-dihydroisoquinolin-1-one; 1,2-Dihydro-7-fluoro-6-hydroxy-1-isoquinolinone; 7-Fluoro-6-hydroxy-2H-isoquinolin-1-one; Fluoro-hydroxy isoquinolinone intermediate; FHOIQ
EINECS	Contact for details

Quality Control

Our 1(2H)-Isoquinolinone, 7-Fluoro-6-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.