Description

(S)-Benzyl (1-(1H-Benzo[D][1,2,3]Triazol-1-Yl)-3-(1H-Indol-3-Yl)-1-Oxopropan-2-Yl)Carbamate is a sophisticated chiral building block and advanced pharmaceutical intermediate of significant interest in modern synthetic chemistry. Its molecular architecture, featuring both indole and benzotriazole moieties, makes it a valuable precursor for the development of novel bioactive compounds. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules, including potential drug candidates targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and anticancer agents.
• Peptidomimetic Research: Serves as a constrained amino acid derivative for constructing peptide analogs and mimetics to study protein-protein interactions.
• Protease Inhibitor Development: Used as a core structure in the design and synthesis of inhibitors for various protease enzymes.
• Asymmetric Synthesis: Employed in stereoselective synthesis routes to introduce chiral centers with high enantiomeric purity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for investigating biological pathways and target validation.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.

Basic Information

Product Name	(S)-Benzyl (1-(1H-Benzo[D][1,2,3]Triazol-1-Yl)-3-(1H-Indol-3-Yl)-1-Oxopropan-2-Yl)Carbamate
CAS No.	850232-59-6
Molecular Formula	C25H21N5O3
Molecular Weight	439.47 g/mol
Synonyms	(S)-Benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamate; (S)-Benzyl (1-(1H-Benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate; (S)-Benzyl N-[1-(1H-benzotriazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate; Benzyl (S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamate; Carbamic acid, N-[1-(1H-benzotriazol-1-yl)-3-(1H-indol-3-yl)-1-oxo-2-propanyl]-, phenylmethyl ester, (S)-; Benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate (S-enantiomer); (S)-Benzyl 1-(benzotriazol-1-yl)-3-(indol-3-yl)-1-oxopropan-2-ylcarbamate
EINECS	Contact for details

Quality Control

Our production of (S)-Benzyl (1-(1H-Benzo[D][1,2,3]Triazol-1-Yl)-3-(1H-Indol-3-Yl)-1-Oxopropan-2-Yl)Carbamate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting its use in cGMP-compliant research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.