Description

Diethyl [2-(Indol-3-Yl)-2-Oxoethyl]Phosphonate is a specialized organophosphorus compound featuring a unique indole-acetylphosphonate structure. This molecular architecture makes it a valuable key synthetic intermediate for constructing complex heterocyclic frameworks. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams engaged in developing novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides and plant growth regulators that leverage the indole moiety.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating advanced polymers with specific optical or electronic properties.
• Academic & Discovery Chemistry: Employed in organic methodology development for constructing C-P and C-C bonds in complex molecule synthesis.
• Bioconjugation Chemistry: The reactive phosphonate group can be utilized for linking biomolecules to other entities in probe development.

Basic Information

Product Name	Diethyl [2-(Indol-3-Yl)-2-Oxoethyl]Phosphonate
CAS No.	850231-86-6
Molecular Formula	C₁₄H₁₈NO₄P
Molecular Weight	295.27 g/mol
Synonyms	Diethyl (2-Oxo-2-(1H-indol-3-yl)ethyl)phosphonate; (2-(1H-Indol-3-yl)-2-oxoethyl)phosphonic Acid Diethyl Ester; 2-(1H-Indol-3-yl)-2-oxoethanephosphonic Acid Diethyl Ester; Diethyl (2-Oxo-2-indol-3-ylethyl)phosphonate; 850231-86-6; AE-848/34359041; AKOS040759630; ZINC000095049791
EINECS	Contact for details

Quality Control

Our Diethyl [2-(Indol-3-Yl)-2-Oxoethyl]Phosphonate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.