Description

(3As,6Ar)-1-Benzyloctahydropyrrolo[2,3-B]Pyrrole CAS NO 850209-63-1 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrrole class of bicyclic heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates targeting neurological disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures, leveraging its rigid bicyclic scaffold and nitrogen functionalities.
• Research & Development (R&D): Essential for academic and industrial research in developing new pharmacophores and exploring structure-activity relationships (SAR).
• Pre-clinical & Clinical Trial Material: Sourced for the production of batches required for pre-clinical studies and early-phase clinical trials under GMP-like conditions.
• Ligand & Catalyst Development: Potential utility in asymmetric synthesis as a precursor for chiral ligands or organocatalysts.

Basic Information

Product Name	(3As,6Ar)-1-Benzyloctahydropyrrolo[2,3-B]Pyrrole
CAS No.	850209-63-1
Molecular Formula	C15H20N2
Molecular Weight	228.33 g/mol
Synonyms	1-Benzyl-(3aR,6aR)-hexahydro-1H-pyrrolo[2,3-b]pyrrole; (3aR,6aR)-1-Benzyloctahydro-1H-pyrrolo[2,3-b]pyrrole; (3aR,6aR)-1-Benzylhexahydropyrrolo[2,3-b]pyrrole; 1H-Pyrrolo[2,3-b]pyrrole, 1-benzyloctahydro-, (3aR,6aR)-; Bicyclic Pyrrolidine Derivative; Benzyl-protected Pyrrolopyrrolidine; Chiral Pyrrolopyrrole Intermediate
EINECS	Contact for details

Quality Control

Our (3As,6Ar)-1-Benzyloctahydropyrrolo[2,3-B]Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.