Description

Cyclopenten-1-Ylboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology in pharmaceutical and advanced materials research. This high-purity intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those containing cyclopentene or related saturated ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific cyclic structures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical coupling partner for introducing the cyclopentenyl moiety into biaryl and heterobiaryl systems.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry & Scale-Up: Provides a reliable and scalable route for the production of target molecules at pilot plant and manufacturing scales.

Basic Information

Product Name	Cyclopenten-1-Ylboronic Acid
CAS No.	850036-28-1
Molecular Formula	C5H9BO2
Molecular Weight	111.94 g/mol
Synonyms	1-Cyclopenten-1-ylboronic Acid; (Cyclopent-1-en-1-yl)boronic Acid; Cyclopent-1-ene-1-boronic Acid; 1-Cyclopentenylboronic Acid; Cyclopentenylboronic Acid; 1-Boronic acid-1-cyclopentene; Cyclopent-1-enylboronic Acid
EINECS	Contact for details

Quality Control

Our Cyclopenten-1-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC for purity assessment, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and oxidizable nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.