Description

6-Chloro-1-Ethoxycarbonyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Employed in the creation of chemical probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic systems in custom synthesis and contract manufacturing.

Basic Information

Product Name	6-Chloro-1-Ethoxycarbonyl-7-Azaindole
CAS No.	849068-50-4
Molecular Formula	C12H11ClN2O2
Molecular Weight	250.68 g/mol
Synonyms	1-(Ethoxycarbonyl)-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid ethyl ester; Ethyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 6-Chloro-1-ethoxycarbonyl-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1-carbethoxy-7-azaindole; 6-Chloro-7-azaindole-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Ethoxycarbonyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.