Description

3-Amino-4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block characterized by its thiophene core, trifluoromethyl group, and carboxylic acid functionality. This compound is essential for advanced research and development, offering a unique combination of structural motifs that enable the synthesis of complex molecules with tailored properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for applications in drug discovery, crop protection, and specialty polymer development.

Application

• Pharmaceutical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Key building block in agrochemical research for developing new herbicides and fungicides with enhanced efficacy.
• Precursor for advanced materials, including organic semiconductors and liquid crystals, leveraging the electron-withdrawing trifluoromethyl group.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Intermediate for synthesizing dyes, pigments, and other specialty fine chemicals.
• Research chemical for academic and industrial studies in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	3-Amino-4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carboxylic Acid
CAS No.	849066-52-0
Molecular Formula	C12H8F3NO2S
Molecular Weight	287.26 g/mol
Synonyms	3-Amino-4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-amino-4-phenyl-5-(trifluoromethyl)-; 849066-52-0; 3-Amino-4-phenyl-5-trifluoromethylthiophene-2-carboxylic acid; 5-(Trifluoromethyl)-3-amino-4-phenylthiophene-2-carboxylic acid; 4-Phenyl-3-amino-5-trifluoromethylthiophene-2-carboxylic acid; 3-Amino-4-phenyl-α,α,α-trifluoro-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Amino-4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We operate under a cGMP-compliant quality system to meet the exacting standards of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.