Description

Ethyl 5-Fluoro-7-(Methylsulphonyl)-1H-Indole-2-Carboxylate is a high-purity, fluorinated indole derivative that serves as a critical advanced intermediate in modern synthetic chemistry. This compound is valued for its unique molecular architecture, which incorporates both a fluorine atom and a methylsulfonyl group, making it a versatile building block for constructing complex pharmacophores. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indole scaffold.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and other transformations to introduce the 5-fluoro-7-(methylsulfonyl)indole moiety into more complex molecules.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique electronic or optical properties.
• Academic & Contract Research: Serves as a standard or reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and discovery chemistry.

Basic Information

Product Name	Ethyl 5-Fluoro-7-(Methylsulphonyl)-1H-Indole-2-Carboxylate
CAS No.	849035-86-5
Molecular Formula	C12H12FNO4S
Molecular Weight	285.29 g/mol
Synonyms	Ethyl 5-Fluoro-7-(Methylsulfonyl)-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-fluoro-7-(methylsulfonyl)-, ethyl ester; 5-Fluoro-7-(methylsulfonyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-Fluoro-7-methanesulfonyl-1H-indole-2-carboxylate; 849035-86-5; 5-Fluoro-7-methylsulfonylindole-2-carboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Our production of Ethyl 5-Fluoro-7-(Methylsulphonyl)-1H-Indole-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.