Description

Ethyl 7-Fluoro-5-(Methylsulfonyl)-1H-Indole-2-Carboxylate is a high-value, multi-functional indole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the strategic combination of a fluorinated indole scaffold with an electron-withdrawing methylsulfonyl group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require sophisticated building blocks for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas, leveraging its fluorinated indole core.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the fluorine atom and sulfone moiety enhance biological activity and environmental stability.
• Material Science: Serves as a specialized monomer or additive in the research of advanced polymers and organic electronic materials due to its unique electronic properties.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Bioconjugation & Probe Development: Utilized in medicinal chemistry for creating fluorescent probes or targeted bioconjugates for diagnostic and biochemical research applications.

Basic Information

Product Name	Ethyl 7-Fluoro-5-(Methylsulfonyl)-1H-Indole-2-Carboxylate
CAS No.	849035-83-2
Molecular Formula	C₁₂H₁₂FNO₄S
Molecular Weight	285.29 g/mol
Synonyms	Ethyl 7-Fluoro-5-(Methylsulfonyl)-1H-Indole-2-Carboxylate; 1H-Indole-2-carboxylic acid, 7-fluoro-5-(methylsulfonyl)-, ethyl ester; 7-Fluoro-5-(methylsulfonyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 7-fluoro-5-methanesulfonyl-1H-indole-2-carboxylate; 849035-83-2; 7-Fluoro-5-methylsulfonylindole-2-carboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Every batch of Ethyl 7-Fluoro-5-(Methylsulfonyl)-1H-Indole-2-Carboxylate is produced and tested under strict quality management protocols to ensure consistency and purity for research and development purposes. Our standard quality commitment includes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.