Description

1,8-Dichloroisoquinoline is a versatile halogenated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its dual reactive sites, enabling selective functionalization for constructing complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the isoquinoline scaffold for bioactivity.
• Material Science: Building block for creating specialized ligands, organic semiconductors, and functional polymers.
• Chemical Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce diverse functionalities.
• Academic & R&D: Serves as a standard reagent in methodological studies and for exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1,8-Dichloroisoquinoline
CAS No.	848841-64-5
Molecular Formula	C9H5Cl2N
Molecular Weight	198.05 g/mol
Synonyms	Isoquinoline, 1,8-dichloro-; 1,8-Dichloro-isoquinoline; 848841-64-5; 1,8-DCIQ; NSC 405124; 1,8-Bis(chloro)isoquinoline; 1,8-Dichloroisoquinoline
EINECS	Contact for details

Quality Control

Our 1,8-Dichloroisoquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.