Description

1-Chloro-4-Isoquinolinyl Boronic Acid is a high-purity, functionalized heterocyclic boronic acid derivative. This compound serves as a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds through cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex isoquinoline-based drug candidates.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for catalysts or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors for biological target validation.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for creating bespoke compound libraries for screening.

Basic Information

Product Name	1-Chloro-4-Isoquinolinyl Boronic Acid
CAS No.	848841-48-5
Molecular Formula	C9H7BClNO2
Molecular Weight	207.42 g/mol
Synonyms	1-Chloro-4-isoquinolineboronic acid; (1-Chloro-4-isoquinolinyl)boronic acid; 1-Chloro-isoquinolin-4-ylboronic acid; 4-Borono-1-chloroisoquinoline; 1-Chloro-4-boronoisoquinoline; B-(1-Chloro-4-isoquinolinyl)boronic acid; 848841-48-5
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Isoquinolinyl Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.